Two New Aryltetralin Lignans from the Roots of Dolomiaea souliei

Two new aryltetralin-type lignans, dolomiaeasin A (1) and dolomiaeasin B (2), were isolated from the roots of Dolomiaea souliei. Their structures were elucidated by means of various spectroscopic analyses. The cytotoxicities of 1 and 2 were tested by the MTT method, and both compounds showed no sign...

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Detalles Bibliográficos
Autores principales: Wei, Hua, He, Chunnian, Peng, Yong, Zhang, Sen, Chen, Xiaoguang, Xiao, Peigen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268169/
https://www.ncbi.nlm.nih.gov/pubmed/22572936
http://dx.doi.org/10.3390/molecules17055544
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author Wei, Hua
He, Chunnian
Peng, Yong
Zhang, Sen
Chen, Xiaoguang
Xiao, Peigen
author_facet Wei, Hua
He, Chunnian
Peng, Yong
Zhang, Sen
Chen, Xiaoguang
Xiao, Peigen
author_sort Wei, Hua
collection PubMed
description Two new aryltetralin-type lignans, dolomiaeasin A (1) and dolomiaeasin B (2), were isolated from the roots of Dolomiaea souliei. Their structures were elucidated by means of various spectroscopic analyses. The cytotoxicities of 1 and 2 were tested by the MTT method, and both compounds showed no significant cytotoxic activities against the A549 and A2780 human cancer cell lines. This is the first time that aryltetralin-type lignans were isolated from the genus Dolomiaea.
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spelling pubmed-62681692018-12-20 Two New Aryltetralin Lignans from the Roots of Dolomiaea souliei Wei, Hua He, Chunnian Peng, Yong Zhang, Sen Chen, Xiaoguang Xiao, Peigen Molecules Article Two new aryltetralin-type lignans, dolomiaeasin A (1) and dolomiaeasin B (2), were isolated from the roots of Dolomiaea souliei. Their structures were elucidated by means of various spectroscopic analyses. The cytotoxicities of 1 and 2 were tested by the MTT method, and both compounds showed no significant cytotoxic activities against the A549 and A2780 human cancer cell lines. This is the first time that aryltetralin-type lignans were isolated from the genus Dolomiaea. MDPI 2012-05-09 /pmc/articles/PMC6268169/ /pubmed/22572936 http://dx.doi.org/10.3390/molecules17055544 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Wei, Hua
He, Chunnian
Peng, Yong
Zhang, Sen
Chen, Xiaoguang
Xiao, Peigen
Two New Aryltetralin Lignans from the Roots of Dolomiaea souliei
title Two New Aryltetralin Lignans from the Roots of Dolomiaea souliei
title_full Two New Aryltetralin Lignans from the Roots of Dolomiaea souliei
title_fullStr Two New Aryltetralin Lignans from the Roots of Dolomiaea souliei
title_full_unstemmed Two New Aryltetralin Lignans from the Roots of Dolomiaea souliei
title_short Two New Aryltetralin Lignans from the Roots of Dolomiaea souliei
title_sort two new aryltetralin lignans from the roots of dolomiaea souliei
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268169/
https://www.ncbi.nlm.nih.gov/pubmed/22572936
http://dx.doi.org/10.3390/molecules17055544
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