Two New Cholic Acid Derivatives from the Marine Ascidian-Associated Bacterium Hasllibacter halocynthiae

The investigation of secondary metabolites in liquid cultures of a recently discovered marine bacterium, Hasllibacter halocynthiae strain KME 002(T), led to the isolation of two new cholic acid derivatives. The structures of these compounds were determined to be 3,3,12-trihydroxy-7-ketocholanic acid...

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Autores principales: Kim, Sung Hun, Shin, Yun Kyung, Sohn, Young Chang, Kwon, Hak Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268207/
https://www.ncbi.nlm.nih.gov/pubmed/23090017
http://dx.doi.org/10.3390/molecules171012357
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author Kim, Sung Hun
Shin, Yun Kyung
Sohn, Young Chang
Kwon, Hak Cheol
author_facet Kim, Sung Hun
Shin, Yun Kyung
Sohn, Young Chang
Kwon, Hak Cheol
author_sort Kim, Sung Hun
collection PubMed
description The investigation of secondary metabolites in liquid cultures of a recently discovered marine bacterium, Hasllibacter halocynthiae strain KME 002(T), led to the isolation of two new cholic acid derivatives. The structures of these compounds were determined to be 3,3,12-trihydroxy-7-ketocholanic acid (1) and 3,3,12-trihydroxy-7-deoxycholanic acid (2) through HRFABMS and NMR data analyses.
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spelling pubmed-62682072018-12-12 Two New Cholic Acid Derivatives from the Marine Ascidian-Associated Bacterium Hasllibacter halocynthiae Kim, Sung Hun Shin, Yun Kyung Sohn, Young Chang Kwon, Hak Cheol Molecules Article The investigation of secondary metabolites in liquid cultures of a recently discovered marine bacterium, Hasllibacter halocynthiae strain KME 002(T), led to the isolation of two new cholic acid derivatives. The structures of these compounds were determined to be 3,3,12-trihydroxy-7-ketocholanic acid (1) and 3,3,12-trihydroxy-7-deoxycholanic acid (2) through HRFABMS and NMR data analyses. MDPI 2012-10-22 /pmc/articles/PMC6268207/ /pubmed/23090017 http://dx.doi.org/10.3390/molecules171012357 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Kim, Sung Hun
Shin, Yun Kyung
Sohn, Young Chang
Kwon, Hak Cheol
Two New Cholic Acid Derivatives from the Marine Ascidian-Associated Bacterium Hasllibacter halocynthiae
title Two New Cholic Acid Derivatives from the Marine Ascidian-Associated Bacterium Hasllibacter halocynthiae
title_full Two New Cholic Acid Derivatives from the Marine Ascidian-Associated Bacterium Hasllibacter halocynthiae
title_fullStr Two New Cholic Acid Derivatives from the Marine Ascidian-Associated Bacterium Hasllibacter halocynthiae
title_full_unstemmed Two New Cholic Acid Derivatives from the Marine Ascidian-Associated Bacterium Hasllibacter halocynthiae
title_short Two New Cholic Acid Derivatives from the Marine Ascidian-Associated Bacterium Hasllibacter halocynthiae
title_sort two new cholic acid derivatives from the marine ascidian-associated bacterium hasllibacter halocynthiae
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268207/
https://www.ncbi.nlm.nih.gov/pubmed/23090017
http://dx.doi.org/10.3390/molecules171012357
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