Design, Synthesis, Antinociceptive and Anti-Inflammatory Activities of Novel Piroxicam Analogues

In this paper we report the design, synthesis, antinociceptive and anti-inflammatory activities of a series of benzothiazine N-acylhydrazones 14a–h, planned by structural modification of piroxicam (1), a non steroidal anti-inflammatory drug. Among the synthesized analogues, compounds 14f (LASSBio-16...

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Detalles Bibliográficos
Autores principales: de Miranda, Amanda Silva, Júnior, Walfrido Bispo, da Silva, Yolanda Karla Cupertino, Alexandre-Moreira, Magna Suzana, Castro, Rosane de Paula, Sabino, José Ricardo, Lião, Luciano Morais, Lima, Lídia Moreira, Barreiro, Eliezer J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268254/
https://www.ncbi.nlm.nih.gov/pubmed/23192189
http://dx.doi.org/10.3390/molecules171214126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268254/
https://www.ncbi.nlm.nih.gov/pubmed/23192189
http://dx.doi.org/10.3390/molecules171214126

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