Improved Methods for Thermal Rearrangement of Alicyclic α-Hydroxyimines to α-Aminoketones: Synthesis of Ketamine Analogues as Antisepsis Candidates

Ketamine is an analgesic/anesthetic drug, which, in combination with other drugs, has been used as anesthetic for over 40 years. Ketamine induces its analgesic activities by blocking the N-methyl-D-aspartate (NMDA) receptor in the central nervous system (CNS). We have reported that low doses of keta...

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Detalles Bibliográficos
Autores principales: Elhawi, Hagit, Eini, Hadar, Douvdevani, Amos, Byk, Gerardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268261/
https://www.ncbi.nlm.nih.gov/pubmed/22664467
http://dx.doi.org/10.3390/molecules17066784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268261/
https://www.ncbi.nlm.nih.gov/pubmed/22664467
http://dx.doi.org/10.3390/molecules17066784

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