Two New Cyanogenic Glucosides from the Leaves of Hydrangea macrophylla

Chemical investigation of the ethanol extract of the aerial parts of Hydrangea macrophylla collected in the Sichuan Province of China resulted in the isolation of two new cyanogenic glucosides. Their structures were elucidated as [(2R)-2-(β-D-glucopyranosyloxy)-2-(3,4-dimethoxy-phenyl)] acetonitrile...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Chun-Juan, Wang, Zhi-Bin, Zhu, Da-Ling, Yu, Ying, Lei, Yin-Ting, Liu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268311/
https://www.ncbi.nlm.nih.gov/pubmed/22569418
http://dx.doi.org/10.3390/molecules17055396
_version_ 1783376257678835712
author Yang, Chun-Juan
Wang, Zhi-Bin
Zhu, Da-Ling
Yu, Ying
Lei, Yin-Ting
Liu, Yan
author_facet Yang, Chun-Juan
Wang, Zhi-Bin
Zhu, Da-Ling
Yu, Ying
Lei, Yin-Ting
Liu, Yan
author_sort Yang, Chun-Juan
collection PubMed
description Chemical investigation of the ethanol extract of the aerial parts of Hydrangea macrophylla collected in the Sichuan Province of China resulted in the isolation of two new cyanogenic glucosides. Their structures were elucidated as [(2R)-2-(β-D-glucopyranosyloxy)-2-(3,4-dimethoxy-phenyl)] acetonitrile (1) and {(2R)-2-[α-D-glucopyranosyl(1→6)β-D-glucopyranosyloxy]-2-(3-hydroxy-4-methoxy-phenyl)}acetonitrile (2) on the basis of extensive spectroscopic analysis (1D, 2D NMR and HRESIMS) and chemical studies.
format Online
Article
Text
id pubmed-6268311
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-62683112018-12-20 Two New Cyanogenic Glucosides from the Leaves of Hydrangea macrophylla Yang, Chun-Juan Wang, Zhi-Bin Zhu, Da-Ling Yu, Ying Lei, Yin-Ting Liu, Yan Molecules Article Chemical investigation of the ethanol extract of the aerial parts of Hydrangea macrophylla collected in the Sichuan Province of China resulted in the isolation of two new cyanogenic glucosides. Their structures were elucidated as [(2R)-2-(β-D-glucopyranosyloxy)-2-(3,4-dimethoxy-phenyl)] acetonitrile (1) and {(2R)-2-[α-D-glucopyranosyl(1→6)β-D-glucopyranosyloxy]-2-(3-hydroxy-4-methoxy-phenyl)}acetonitrile (2) on the basis of extensive spectroscopic analysis (1D, 2D NMR and HRESIMS) and chemical studies. MDPI 2012-05-08 /pmc/articles/PMC6268311/ /pubmed/22569418 http://dx.doi.org/10.3390/molecules17055396 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Yang, Chun-Juan
Wang, Zhi-Bin
Zhu, Da-Ling
Yu, Ying
Lei, Yin-Ting
Liu, Yan
Two New Cyanogenic Glucosides from the Leaves of Hydrangea macrophylla
title Two New Cyanogenic Glucosides from the Leaves of Hydrangea macrophylla
title_full Two New Cyanogenic Glucosides from the Leaves of Hydrangea macrophylla
title_fullStr Two New Cyanogenic Glucosides from the Leaves of Hydrangea macrophylla
title_full_unstemmed Two New Cyanogenic Glucosides from the Leaves of Hydrangea macrophylla
title_short Two New Cyanogenic Glucosides from the Leaves of Hydrangea macrophylla
title_sort two new cyanogenic glucosides from the leaves of hydrangea macrophylla
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268311/
https://www.ncbi.nlm.nih.gov/pubmed/22569418
http://dx.doi.org/10.3390/molecules17055396
work_keys_str_mv AT yangchunjuan twonewcyanogenicglucosidesfromtheleavesofhydrangeamacrophylla
AT wangzhibin twonewcyanogenicglucosidesfromtheleavesofhydrangeamacrophylla
AT zhudaling twonewcyanogenicglucosidesfromtheleavesofhydrangeamacrophylla
AT yuying twonewcyanogenicglucosidesfromtheleavesofhydrangeamacrophylla
AT leiyinting twonewcyanogenicglucosidesfromtheleavesofhydrangeamacrophylla
AT liuyan twonewcyanogenicglucosidesfromtheleavesofhydrangeamacrophylla

Ejemplares similares