Studies on the Interaction Mechanism of Pyrene Derivatives with Human Tumor-Related DNA

Pyrene derivatives can be carcinogenic, teratogenic and mutagenic, thus having the potential to cause malignant diseases. In this work, the interactions of two selected pyrene derivatives (1-OHP and 1-PBO) and human tumor-related DNA (p53 DNA and C-myc DNA) are investigated by spectroscopic and non-...

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Detalles Bibliográficos
Autores principales: Li, Li, Lu, Jia, Xu, Chongzheng, Li, Huihui, Yang, Xiaodi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268327/
https://www.ncbi.nlm.nih.gov/pubmed/23192191
http://dx.doi.org/10.3390/molecules171214159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268327/
https://www.ncbi.nlm.nih.gov/pubmed/23192191
http://dx.doi.org/10.3390/molecules171214159

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