Cargando…
Synthesis and Biological Evaluation of Thiophene Derivatives as Acetylcholinesterase Inhibitors
A series of new thiophene derivatives has been synthesized using the Gewald protocol. The acetylcholinesterase inhibition activity was assayed according to Ellman’s method using donepezil as reference. Some of the compounds were found to be more potent inhibitors than the reference. 2-(2-(4-(4-Metho...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268334/ https://www.ncbi.nlm.nih.gov/pubmed/22692245 http://dx.doi.org/10.3390/molecules17067217 |