A New Iridoid Glycoside from the Roots of Dipsacus asper

A new iridoid glycoside, named loganic acid ethyl ester (1), together with five known compounds: chlorogenic acid (2), caffeic acid (3), loganin (4), cantleyoside (5) and syringaresinol-4′,4′′-O-bis-β-D-glucoside (6) were isolated from the roots of Dipsacus asper. The structure of compound 1 was elu...

Descripción completa

Detalles Bibliográficos
Autores principales: Ji, De, Zhang, Chunfeng, Li, Jingzhi, Yang, Haowei, Shen, Jingyang, Yang, Zhonglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268358/
https://www.ncbi.nlm.nih.gov/pubmed/22306831
http://dx.doi.org/10.3390/molecules17021419
Descripción
Sumario:A new iridoid glycoside, named loganic acid ethyl ester (1), together with five known compounds: chlorogenic acid (2), caffeic acid (3), loganin (4), cantleyoside (5) and syringaresinol-4′,4′′-O-bis-β-D-glucoside (6) were isolated from the roots of Dipsacus asper. The structure of compound 1 was elucidated on the basis of detailed spectroscopic analyses. Lignan is isolated from Dipsacaceae species for the first time. Compounds 1, 4 and 5 had moderate neuroprotective effects against the Aβ(25–35) induced cell death in PC12 cells.

Ejemplares similares