A New Iridoid Glycoside from the Roots of Dipsacus asper

A new iridoid glycoside, named loganic acid ethyl ester (1), together with five known compounds: chlorogenic acid (2), caffeic acid (3), loganin (4), cantleyoside (5) and syringaresinol-4′,4′′-O-bis-β-D-glucoside (6) were isolated from the roots of Dipsacus asper. The structure of compound 1 was elu...

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Detalles Bibliográficos
Autores principales: Ji, De, Zhang, Chunfeng, Li, Jingzhi, Yang, Haowei, Shen, Jingyang, Yang, Zhonglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268358/
https://www.ncbi.nlm.nih.gov/pubmed/22306831
http://dx.doi.org/10.3390/molecules17021419
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author Ji, De
Zhang, Chunfeng
Li, Jingzhi
Yang, Haowei
Shen, Jingyang
Yang, Zhonglin
author_facet Ji, De
Zhang, Chunfeng
Li, Jingzhi
Yang, Haowei
Shen, Jingyang
Yang, Zhonglin
author_sort Ji, De
collection PubMed
description A new iridoid glycoside, named loganic acid ethyl ester (1), together with five known compounds: chlorogenic acid (2), caffeic acid (3), loganin (4), cantleyoside (5) and syringaresinol-4′,4′′-O-bis-β-D-glucoside (6) were isolated from the roots of Dipsacus asper. The structure of compound 1 was elucidated on the basis of detailed spectroscopic analyses. Lignan is isolated from Dipsacaceae species for the first time. Compounds 1, 4 and 5 had moderate neuroprotective effects against the Aβ(25–35) induced cell death in PC12 cells.
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spelling pubmed-62683582018-12-10 A New Iridoid Glycoside from the Roots of Dipsacus asper Ji, De Zhang, Chunfeng Li, Jingzhi Yang, Haowei Shen, Jingyang Yang, Zhonglin Molecules Article A new iridoid glycoside, named loganic acid ethyl ester (1), together with five known compounds: chlorogenic acid (2), caffeic acid (3), loganin (4), cantleyoside (5) and syringaresinol-4′,4′′-O-bis-β-D-glucoside (6) were isolated from the roots of Dipsacus asper. The structure of compound 1 was elucidated on the basis of detailed spectroscopic analyses. Lignan is isolated from Dipsacaceae species for the first time. Compounds 1, 4 and 5 had moderate neuroprotective effects against the Aβ(25–35) induced cell death in PC12 cells. MDPI 2012-02-03 /pmc/articles/PMC6268358/ /pubmed/22306831 http://dx.doi.org/10.3390/molecules17021419 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Ji, De
Zhang, Chunfeng
Li, Jingzhi
Yang, Haowei
Shen, Jingyang
Yang, Zhonglin
A New Iridoid Glycoside from the Roots of Dipsacus asper
title A New Iridoid Glycoside from the Roots of Dipsacus asper
title_full A New Iridoid Glycoside from the Roots of Dipsacus asper
title_fullStr A New Iridoid Glycoside from the Roots of Dipsacus asper
title_full_unstemmed A New Iridoid Glycoside from the Roots of Dipsacus asper
title_short A New Iridoid Glycoside from the Roots of Dipsacus asper
title_sort new iridoid glycoside from the roots of dipsacus asper
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268358/
https://www.ncbi.nlm.nih.gov/pubmed/22306831
http://dx.doi.org/10.3390/molecules17021419
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