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Design and Synthesis of an (18)F-Labeled Version of Phenylethyl Orvinol ([(18)F]FE-PEO) for PET-Imaging of Opioid Receptors
The semisynthetic oripavine derivative phenethyl orvinol (PEO), a full agonist at opioid receptors (OR), is an attractive structural motif for developing (18)F-labeled PET tracers with a high degree of sensitivity for competition between endogenous and exogenous OR-ligands. The target cold reference...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268392/ https://www.ncbi.nlm.nih.gov/pubmed/23023682 http://dx.doi.org/10.3390/molecules171011554 |