Norcembranoidal Diterpenes from a Formosan Soft Coral Sinularia sp.

Two norcembranoidal diterpenes, 5-episinuleptolide acetate (1) and scabrolide D (2), were isolated from a Formosan octocoral identified as Sinularia sp. The structures of norcembranoids 1 and 2 were established by spectroscopic methods and by comparison of the spectral data with those of known analo...

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Autores principales: Yen, Wei-Hsuan, Hu, Li-Chung, Su, Jui-Hsin, Lu, Mei-Chin, Twan, Wen-Hung, Yang, Show-Ying, Kuo, Yung-Chi, Weng, Ching-Feng, Lee, Chia-Hung, Kuo, Yueh-Hsiung, Sung, Ping-Jyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268393/
https://www.ncbi.nlm.nih.gov/pubmed/23187289
http://dx.doi.org/10.3390/molecules171214058
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author Yen, Wei-Hsuan
Hu, Li-Chung
Su, Jui-Hsin
Lu, Mei-Chin
Twan, Wen-Hung
Yang, Show-Ying
Kuo, Yung-Chi
Weng, Ching-Feng
Lee, Chia-Hung
Kuo, Yueh-Hsiung
Sung, Ping-Jyun
author_facet Yen, Wei-Hsuan
Hu, Li-Chung
Su, Jui-Hsin
Lu, Mei-Chin
Twan, Wen-Hung
Yang, Show-Ying
Kuo, Yung-Chi
Weng, Ching-Feng
Lee, Chia-Hung
Kuo, Yueh-Hsiung
Sung, Ping-Jyun
author_sort Yen, Wei-Hsuan
collection PubMed
description Two norcembranoidal diterpenes, 5-episinuleptolide acetate (1) and scabrolide D (2), were isolated from a Formosan octocoral identified as Sinularia sp. The structures of norcembranoids 1 and 2 were established by spectroscopic methods and by comparison of the spectral data with those of known analogues and 1 was proven to be a new natural product. Norcembranoid 1 was found to exhibit cytotoxicity toward a panel of tumor cells.
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spelling pubmed-62683932018-12-14 Norcembranoidal Diterpenes from a Formosan Soft Coral Sinularia sp. Yen, Wei-Hsuan Hu, Li-Chung Su, Jui-Hsin Lu, Mei-Chin Twan, Wen-Hung Yang, Show-Ying Kuo, Yung-Chi Weng, Ching-Feng Lee, Chia-Hung Kuo, Yueh-Hsiung Sung, Ping-Jyun Molecules Article Two norcembranoidal diterpenes, 5-episinuleptolide acetate (1) and scabrolide D (2), were isolated from a Formosan octocoral identified as Sinularia sp. The structures of norcembranoids 1 and 2 were established by spectroscopic methods and by comparison of the spectral data with those of known analogues and 1 was proven to be a new natural product. Norcembranoid 1 was found to exhibit cytotoxicity toward a panel of tumor cells. MDPI 2012-11-27 /pmc/articles/PMC6268393/ /pubmed/23187289 http://dx.doi.org/10.3390/molecules171214058 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Yen, Wei-Hsuan
Hu, Li-Chung
Su, Jui-Hsin
Lu, Mei-Chin
Twan, Wen-Hung
Yang, Show-Ying
Kuo, Yung-Chi
Weng, Ching-Feng
Lee, Chia-Hung
Kuo, Yueh-Hsiung
Sung, Ping-Jyun
Norcembranoidal Diterpenes from a Formosan Soft Coral Sinularia sp.
title Norcembranoidal Diterpenes from a Formosan Soft Coral Sinularia sp.
title_full Norcembranoidal Diterpenes from a Formosan Soft Coral Sinularia sp.
title_fullStr Norcembranoidal Diterpenes from a Formosan Soft Coral Sinularia sp.
title_full_unstemmed Norcembranoidal Diterpenes from a Formosan Soft Coral Sinularia sp.
title_short Norcembranoidal Diterpenes from a Formosan Soft Coral Sinularia sp.
title_sort norcembranoidal diterpenes from a formosan soft coral sinularia sp.
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268393/
https://www.ncbi.nlm.nih.gov/pubmed/23187289
http://dx.doi.org/10.3390/molecules171214058
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