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A General Synthesis of Bis-indolylpiperazine-2,5-diones
The one-pot synthesis of three dragmacidin derivatives is reported. Sarcosine anhydride (4) is brominated and immediately reacted with the corresponding indole to produce the products, namely 3,6-bis(5′-methoxy-3′-indolyl)-1,4-dimethylpiperazine-2,5-dione (1), 3,6-bis(7′-methyl-3′-indolyl)-1,4-dimet...
Autores principales: | Crooke, Stephen, Whitlock, Christine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268405/ https://www.ncbi.nlm.nih.gov/pubmed/23519256 http://dx.doi.org/10.3390/molecules171214841 |
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