New Furanones from the Plant Endophytic Fungus Pestalotiopsis besseyi

Pestalafuranones A–E (compounds 1–5), five new 2(5H)-furanones, have been isolated from cultures of an isolate of Pestalotiopsis besseyi. The structures of these compounds were elucidated mainly by analysis of their NMR spectroscopic data and HRESIMS experiments. Pestalafuranones A–C (compounds 1–3)...

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Detalles Bibliográficos
Autores principales: Liu, Haitao, Liu, Shuchun, Guo, Liangdong, Zhang, Yonggang, Cui, Langjun, Ding, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268428/
https://www.ncbi.nlm.nih.gov/pubmed/23187285
http://dx.doi.org/10.3390/molecules171214015
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author Liu, Haitao
Liu, Shuchun
Guo, Liangdong
Zhang, Yonggang
Cui, Langjun
Ding, Gang
author_facet Liu, Haitao
Liu, Shuchun
Guo, Liangdong
Zhang, Yonggang
Cui, Langjun
Ding, Gang
author_sort Liu, Haitao
collection PubMed
description Pestalafuranones A–E (compounds 1–5), five new 2(5H)-furanones, have been isolated from cultures of an isolate of Pestalotiopsis besseyi. The structures of these compounds were elucidated mainly by analysis of their NMR spectroscopic data and HRESIMS experiments. Pestalafuranones A–C (compounds 1–3) displayed weak inhibitory effects against HIV-1 replication in C8166 cells, whereas pestalafuranones D (4) and E (5) showed moderate antifungal activity against the plant pathogens Verticillium dahiae and Alternaria longipes.
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spelling pubmed-62684282018-12-14 New Furanones from the Plant Endophytic Fungus Pestalotiopsis besseyi Liu, Haitao Liu, Shuchun Guo, Liangdong Zhang, Yonggang Cui, Langjun Ding, Gang Molecules Article Pestalafuranones A–E (compounds 1–5), five new 2(5H)-furanones, have been isolated from cultures of an isolate of Pestalotiopsis besseyi. The structures of these compounds were elucidated mainly by analysis of their NMR spectroscopic data and HRESIMS experiments. Pestalafuranones A–C (compounds 1–3) displayed weak inhibitory effects against HIV-1 replication in C8166 cells, whereas pestalafuranones D (4) and E (5) showed moderate antifungal activity against the plant pathogens Verticillium dahiae and Alternaria longipes. MDPI 2012-11-27 /pmc/articles/PMC6268428/ /pubmed/23187285 http://dx.doi.org/10.3390/molecules171214015 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Liu, Haitao
Liu, Shuchun
Guo, Liangdong
Zhang, Yonggang
Cui, Langjun
Ding, Gang
New Furanones from the Plant Endophytic Fungus Pestalotiopsis besseyi
title New Furanones from the Plant Endophytic Fungus Pestalotiopsis besseyi
title_full New Furanones from the Plant Endophytic Fungus Pestalotiopsis besseyi
title_fullStr New Furanones from the Plant Endophytic Fungus Pestalotiopsis besseyi
title_full_unstemmed New Furanones from the Plant Endophytic Fungus Pestalotiopsis besseyi
title_short New Furanones from the Plant Endophytic Fungus Pestalotiopsis besseyi
title_sort new furanones from the plant endophytic fungus pestalotiopsis besseyi
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268428/
https://www.ncbi.nlm.nih.gov/pubmed/23187285
http://dx.doi.org/10.3390/molecules171214015
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