Suzuki-Miyaura Reactions Catalyzed by C(2)-Symmetric Pd-Multi-Dentate N-Heterocyclic Carbene Complexes

Suzuki-Miyaura coupling reactions are promoted by Pd complexes ligated with C(2)-symmetric multi-dentate N-heterocyclic carbenes derived in situ from Pd(OAc)(2) and imidazolium salts. Good to excellent yields were obtained for aryl bromides as substrates. Turnover numbers of up to 10(5) could be ach...

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Detalles Bibliográficos
Autores principales: Jiang, Lan, Shan, Fengjun, Li, Zhengning, Zhao, Defeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268461/
https://www.ncbi.nlm.nih.gov/pubmed/23085660
http://dx.doi.org/10.3390/molecules171012121
Descripción
Sumario:Suzuki-Miyaura coupling reactions are promoted by Pd complexes ligated with C(2)-symmetric multi-dentate N-heterocyclic carbenes derived in situ from Pd(OAc)(2) and imidazolium salts. Good to excellent yields were obtained for aryl bromides as substrates. Turnover numbers of up to 10(5) could be achieved with 5 × 10(−4) mol% of Pd(OAc)(2)/1 × 10(−3) mol% NHC precatalyst in 24 h.

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