A Support Vector Machine Classification Model for Benzo[c]phenathridine Analogues with Topoisomerase-I Inhibitory Activity

Benzo[c]phenanthridine (BCP) derivatives were identified as topoisomerase I (TOP-I) targeting agents with pronounced antitumor activity. In this study, a support vector machine model was performed on a series of 73 analogues to classify BCP derivatives according to TOP-I inhibitory activity. The bes...

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Detalles Bibliográficos
Autores principales: Thai, Khac-Minh, Nguyen, Thuy-Quyen, Ngo, Trieu-Du, Tran, Thanh-Dao, Huynh, Thi-Ngoc-Phuong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268465/
https://www.ncbi.nlm.nih.gov/pubmed/22510606
http://dx.doi.org/10.3390/molecules17044560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268465/
https://www.ncbi.nlm.nih.gov/pubmed/22510606
http://dx.doi.org/10.3390/molecules17044560

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