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Regioselectivity in the Ring Opening of Epoxides for the Synthesis of Aminocyclitols from D-(−)-Quinic Acid
Efficient syntheses of four aminocyclitols are reported. Each synthesis is accomplished in eight steps starting from D-(−)-quinic acid. The key step involves a highly regioselective ring opening of epoxides by sodium azide.
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268476/ https://www.ncbi.nlm.nih.gov/pubmed/22508330 http://dx.doi.org/10.3390/molecules17044498 |
| Sumario: | Efficient syntheses of four aminocyclitols are reported. Each synthesis is accomplished in eight steps starting from D-(−)-quinic acid. The key step involves a highly regioselective ring opening of epoxides by sodium azide. |
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