Synthesis of cis- and trans-3-Aminocyclohexanols by Reduction of β-Enaminoketones

We describe a protocol developed for the preparation of β-enaminoketones derived from 1,3-cyclohexanediones, and their subsequent reduction by sodium in THF-isopropyl alcohol to afford cis- and trans-3-aminocyclohexanols.

Detalles Bibliográficos
Autores principales: Balbás, Iris Montoya, Mendoza, Blanca Eda Domínguez, Fernández-Zertuche, Mario, Ordoñez, Mario, Linzaga-Elizalde, Irma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268485/
https://www.ncbi.nlm.nih.gov/pubmed/22202804
http://dx.doi.org/10.3390/molecules17010151
Descripción
Sumario:We describe a protocol developed for the preparation of β-enaminoketones derived from 1,3-cyclohexanediones, and their subsequent reduction by sodium in THF-isopropyl alcohol to afford cis- and trans-3-aminocyclohexanols.

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