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Synthesis of cis- and trans-3-Aminocyclohexanols by Reduction of β-Enaminoketones
We describe a protocol developed for the preparation of β-enaminoketones derived from 1,3-cyclohexanediones, and their subsequent reduction by sodium in THF-isopropyl alcohol to afford cis- and trans-3-aminocyclohexanols.
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268485/ https://www.ncbi.nlm.nih.gov/pubmed/22202804 http://dx.doi.org/10.3390/molecules17010151 |
| _version_ | 1783376297948348416 |
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| author | Balbás, Iris Montoya Mendoza, Blanca Eda Domínguez Fernández-Zertuche, Mario Ordoñez, Mario Linzaga-Elizalde, Irma |
| author_facet | Balbás, Iris Montoya Mendoza, Blanca Eda Domínguez Fernández-Zertuche, Mario Ordoñez, Mario Linzaga-Elizalde, Irma |
| author_sort | Balbás, Iris Montoya |
| collection | PubMed |
| description | We describe a protocol developed for the preparation of β-enaminoketones derived from 1,3-cyclohexanediones, and their subsequent reduction by sodium in THF-isopropyl alcohol to afford cis- and trans-3-aminocyclohexanols. |
| format | Online Article Text |
| id | pubmed-6268485 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2011 |
| publisher | MDPI |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-62684852018-12-11 Synthesis of cis- and trans-3-Aminocyclohexanols by Reduction of β-Enaminoketones Balbás, Iris Montoya Mendoza, Blanca Eda Domínguez Fernández-Zertuche, Mario Ordoñez, Mario Linzaga-Elizalde, Irma Molecules Article We describe a protocol developed for the preparation of β-enaminoketones derived from 1,3-cyclohexanediones, and their subsequent reduction by sodium in THF-isopropyl alcohol to afford cis- and trans-3-aminocyclohexanols. MDPI 2011-12-27 /pmc/articles/PMC6268485/ /pubmed/22202804 http://dx.doi.org/10.3390/molecules17010151 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
| spellingShingle | Article Balbás, Iris Montoya Mendoza, Blanca Eda Domínguez Fernández-Zertuche, Mario Ordoñez, Mario Linzaga-Elizalde, Irma Synthesis of cis- and trans-3-Aminocyclohexanols by Reduction of β-Enaminoketones |
| title | Synthesis of cis- and trans-3-Aminocyclohexanols by Reduction of β-Enaminoketones |
| title_full | Synthesis of cis- and trans-3-Aminocyclohexanols by Reduction of β-Enaminoketones |
| title_fullStr | Synthesis of cis- and trans-3-Aminocyclohexanols by Reduction of β-Enaminoketones |
| title_full_unstemmed | Synthesis of cis- and trans-3-Aminocyclohexanols by Reduction of β-Enaminoketones |
| title_short | Synthesis of cis- and trans-3-Aminocyclohexanols by Reduction of β-Enaminoketones |
| title_sort | synthesis of cis- and trans-3-aminocyclohexanols by reduction of β-enaminoketones |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268485/ https://www.ncbi.nlm.nih.gov/pubmed/22202804 http://dx.doi.org/10.3390/molecules17010151 |
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