Allylation of Functionalized Aldehydes by Potassium Allyltrifluoroborate Catalyzed by 18-Crown-6 in Aqueous Media

An efficient method for the allylation of aldehydes containing a broad range of functional groups using potassium allyltrifluoroborate is described. The reaction utilizes a catalytic amount of 18-C-6 in biphasic media under open atmosphere and room temperature to provide the corresponding homoallyli...

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Autores principales: Barbosa, Fernanda C. G., Freitas, Juliano C. R., Melo, Caio F., Menezes, Paulo H., Oliveira, Roberta A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268519/
https://www.ncbi.nlm.nih.gov/pubmed/23192187
http://dx.doi.org/10.3390/molecules171214099
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author Barbosa, Fernanda C. G.
Freitas, Juliano C. R.
Melo, Caio F.
Menezes, Paulo H.
Oliveira, Roberta A.
author_facet Barbosa, Fernanda C. G.
Freitas, Juliano C. R.
Melo, Caio F.
Menezes, Paulo H.
Oliveira, Roberta A.
author_sort Barbosa, Fernanda C. G.
collection PubMed
description An efficient method for the allylation of aldehydes containing a broad range of functional groups using potassium allyltrifluoroborate is described. The reaction utilizes a catalytic amount of 18-C-6 in biphasic media under open atmosphere and room temperature to provide the corresponding homoallylic alcohols in high yields and without the necessity of any subsequent purification.
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spelling pubmed-62685192018-12-14 Allylation of Functionalized Aldehydes by Potassium Allyltrifluoroborate Catalyzed by 18-Crown-6 in Aqueous Media Barbosa, Fernanda C. G. Freitas, Juliano C. R. Melo, Caio F. Menezes, Paulo H. Oliveira, Roberta A. Molecules Communication An efficient method for the allylation of aldehydes containing a broad range of functional groups using potassium allyltrifluoroborate is described. The reaction utilizes a catalytic amount of 18-C-6 in biphasic media under open atmosphere and room temperature to provide the corresponding homoallylic alcohols in high yields and without the necessity of any subsequent purification. MDPI 2012-11-28 /pmc/articles/PMC6268519/ /pubmed/23192187 http://dx.doi.org/10.3390/molecules171214099 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Communication
Barbosa, Fernanda C. G.
Freitas, Juliano C. R.
Melo, Caio F.
Menezes, Paulo H.
Oliveira, Roberta A.
Allylation of Functionalized Aldehydes by Potassium Allyltrifluoroborate Catalyzed by 18-Crown-6 in Aqueous Media
title Allylation of Functionalized Aldehydes by Potassium Allyltrifluoroborate Catalyzed by 18-Crown-6 in Aqueous Media
title_full Allylation of Functionalized Aldehydes by Potassium Allyltrifluoroborate Catalyzed by 18-Crown-6 in Aqueous Media
title_fullStr Allylation of Functionalized Aldehydes by Potassium Allyltrifluoroborate Catalyzed by 18-Crown-6 in Aqueous Media
title_full_unstemmed Allylation of Functionalized Aldehydes by Potassium Allyltrifluoroborate Catalyzed by 18-Crown-6 in Aqueous Media
title_short Allylation of Functionalized Aldehydes by Potassium Allyltrifluoroborate Catalyzed by 18-Crown-6 in Aqueous Media
title_sort allylation of functionalized aldehydes by potassium allyltrifluoroborate catalyzed by 18-crown-6 in aqueous media
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268519/
https://www.ncbi.nlm.nih.gov/pubmed/23192187
http://dx.doi.org/10.3390/molecules171214099
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