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Synthesis and Biological Activity of 23-Hydroxybetulinic Acid C-28 Ester Derivatives as Antitumor Agent Candidates

23-Hydroxybetulinic acid (1) served as the precursor for the synthesis of C-28 ester derivatives. The target compounds were evaluated in vitro for their antitumor activities against five cell lines (A549, BEL-7402, SF-763, B16 and HL-60). Among the obtained compounds, 6i had the most potent antitumo...

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Detalles Bibliográficos
Autores principales: Bi, Yi, Xu, Jinyi, Sun, Fei, Wu, Xiaoming, Ye, Wencai, Sun, Yijun, Huang, Wenwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268522/
https://www.ncbi.nlm.nih.gov/pubmed/22832884
http://dx.doi.org/10.3390/molecules17088832