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Synthesis and Biological Activity of 23-Hydroxybetulinic Acid C-28 Ester Derivatives as Antitumor Agent Candidates
23-Hydroxybetulinic acid (1) served as the precursor for the synthesis of C-28 ester derivatives. The target compounds were evaluated in vitro for their antitumor activities against five cell lines (A549, BEL-7402, SF-763, B16 and HL-60). Among the obtained compounds, 6i had the most potent antitumo...
Autores principales: | Bi, Yi, Xu, Jinyi, Sun, Fei, Wu, Xiaoming, Ye, Wencai, Sun, Yijun, Huang, Wenwen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268522/ https://www.ncbi.nlm.nih.gov/pubmed/22832884 http://dx.doi.org/10.3390/molecules17088832 |
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