A Facile Synthesis for Novel Loperamide Analogs as Potential μ Opioid Receptor Agonists

A facile synthesis for novel loperamide analogs as potential μ opioid receptors is described. The synthetic procedure for compound 5, which contains two 4-phenyl piperidine scaffolds, was optimized, and this compound was synthesized in excellent yield. We also describe a mild and highly efficient pr...

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Detalles Bibliográficos
Autores principales: Bao, Xiaofeng, Liu, Duliang, Jin, Yanyan, Yang, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268526/
https://www.ncbi.nlm.nih.gov/pubmed/23208464
http://dx.doi.org/10.3390/molecules171214288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268526/
https://www.ncbi.nlm.nih.gov/pubmed/23208464
http://dx.doi.org/10.3390/molecules171214288

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