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A Facile Synthesis for Novel Loperamide Analogs as Potential μ Opioid Receptor Agonists
A facile synthesis for novel loperamide analogs as potential μ opioid receptors is described. The synthetic procedure for compound 5, which contains two 4-phenyl piperidine scaffolds, was optimized, and this compound was synthesized in excellent yield. We also describe a mild and highly efficient pr...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268526/ https://www.ncbi.nlm.nih.gov/pubmed/23208464 http://dx.doi.org/10.3390/molecules171214288 |