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Synthesis of Azanucleosides through Regioselective Ring-Opening of Epoxides Catalyzed by Sulphated Zirconia under Microwave and Solvent-Free Conditions
New azanucleosides were obtained using sulphated zirconia (ZS) as catalyst in the nucleophilic oxirane ring opening reaction of 1-allyl-3-(oxiran-2-ylmethyl)pyrimidine-2,4(1H,3H)-dione and 1-allyl-5-methyl-3-(oxiran-2-ylmethyl)-pyrimidine-2,4(1H,3H)-dione, with (S)-prolinol. The new templates were o...
Autores principales: | Hernández-Reyes, Celia Xochitl, Angeles-Beltrán, Deyanira, Lomas-Romero, Leticia, González-Zamora, Eduardo, Gaviño, Rubén, Cárdenas, Jorge, Morales-Serna, José Antonio, Negrón-Silva, Guillermo E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268552/ https://www.ncbi.nlm.nih.gov/pubmed/22421790 http://dx.doi.org/10.3390/molecules17033359 |
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