An Efficient One-Pot Synthesis of Pyrano[3,2-c]quinolin-2,5-dione Derivatives Catalyzed by L-Proline

A series of 4-aryl-6-methyl-3,4-dihydro-2H-pyrano[3,2-c]quinolin-2,5(6H)-diones were synthesized via the three-component reactions of aromatic aldehydes, 4-hydroxy-1-methylquinolin-2(1H)-one, and Meldrum’s acid catalyzed by L-proline. The structures of the products were identified by spectroscopic a...

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Detalles Bibliográficos
Autores principales: Zhu, Songlei, Wang, Jing, Xu, Zhou, Li, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268561/
https://www.ncbi.nlm.nih.gov/pubmed/23174901
http://dx.doi.org/10.3390/molecules171213856
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author Zhu, Songlei
Wang, Jing
Xu, Zhou
Li, Jie
author_facet Zhu, Songlei
Wang, Jing
Xu, Zhou
Li, Jie
author_sort Zhu, Songlei
collection PubMed
description A series of 4-aryl-6-methyl-3,4-dihydro-2H-pyrano[3,2-c]quinolin-2,5(6H)-diones were synthesized via the three-component reactions of aromatic aldehydes, 4-hydroxy-1-methylquinolin-2(1H)-one, and Meldrum’s acid catalyzed by L-proline. The structures of the products were identified by spectroscopic analysis. A mechanism for this three-component reaction catalyzed by L-proline was proposed.
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spelling pubmed-62685612018-12-14 An Efficient One-Pot Synthesis of Pyrano[3,2-c]quinolin-2,5-dione Derivatives Catalyzed by L-Proline Zhu, Songlei Wang, Jing Xu, Zhou Li, Jie Molecules Article A series of 4-aryl-6-methyl-3,4-dihydro-2H-pyrano[3,2-c]quinolin-2,5(6H)-diones were synthesized via the three-component reactions of aromatic aldehydes, 4-hydroxy-1-methylquinolin-2(1H)-one, and Meldrum’s acid catalyzed by L-proline. The structures of the products were identified by spectroscopic analysis. A mechanism for this three-component reaction catalyzed by L-proline was proposed. MDPI 2012-11-22 /pmc/articles/PMC6268561/ /pubmed/23174901 http://dx.doi.org/10.3390/molecules171213856 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Zhu, Songlei
Wang, Jing
Xu, Zhou
Li, Jie
An Efficient One-Pot Synthesis of Pyrano[3,2-c]quinolin-2,5-dione Derivatives Catalyzed by L-Proline
title An Efficient One-Pot Synthesis of Pyrano[3,2-c]quinolin-2,5-dione Derivatives Catalyzed by L-Proline
title_full An Efficient One-Pot Synthesis of Pyrano[3,2-c]quinolin-2,5-dione Derivatives Catalyzed by L-Proline
title_fullStr An Efficient One-Pot Synthesis of Pyrano[3,2-c]quinolin-2,5-dione Derivatives Catalyzed by L-Proline
title_full_unstemmed An Efficient One-Pot Synthesis of Pyrano[3,2-c]quinolin-2,5-dione Derivatives Catalyzed by L-Proline
title_short An Efficient One-Pot Synthesis of Pyrano[3,2-c]quinolin-2,5-dione Derivatives Catalyzed by L-Proline
title_sort efficient one-pot synthesis of pyrano[3,2-c]quinolin-2,5-dione derivatives catalyzed by l-proline
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268561/
https://www.ncbi.nlm.nih.gov/pubmed/23174901
http://dx.doi.org/10.3390/molecules171213856
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