Benzoylated Uronic Acid Building Blocks and Synthesis of N-Uronate Conjugates of Lamotrigine

A chemoenzymatic approach towards benzoylated uronic acid building blocks has been investigated starting with benzoylated hexapyranosides using regioselective C-6 enzymatic hydrolysis as the key step. Two of the building blocks were reacted with the antiepileptic drug lamotrigine. Glucuronidation of...

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Detalles Bibliográficos
Autores principales: Esmurziev, Aslan M., Reimers, Arne, Andreassen, Trygve, Simic, Nebojsa, Sundby, Eirik, Hoff, Bård Helge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268592/
https://www.ncbi.nlm.nih.gov/pubmed/22269868
http://dx.doi.org/10.3390/molecules17010820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268592/
https://www.ncbi.nlm.nih.gov/pubmed/22269868
http://dx.doi.org/10.3390/molecules17010820

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