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Synthesis and Preliminary Investigations of the siRNA Delivery Potential of Novel, Single-Chain Rigid Cationic Carotenoid Lipids

The success of nucleic acid delivery requires the development of safe and efficient delivery vectors that overcome cellular barriers for effective transport. Herein we describe the synthesis of a series of novel, single-chain rigid cationic carotenoid lipids and a study of their preliminary in vitro...

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Detalles Bibliográficos
Autores principales: Pungente, Michael D., Jubeli, Emile, Øpstad, Christer L., Al-Kawaz, Mais, Barakat, Nour, Ibrahim, Tarek, Khalique, Nada Abdul, Raju, Liji, Jones, Rachel, Leopold, Philip L., Sliwka, Hans-Richard, Partali, Vassilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268619/
https://www.ncbi.nlm.nih.gov/pubmed/22426529
http://dx.doi.org/10.3390/molecules17033484