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Synthesis and Preliminary Investigations of the siRNA Delivery Potential of Novel, Single-Chain Rigid Cationic Carotenoid Lipids
The success of nucleic acid delivery requires the development of safe and efficient delivery vectors that overcome cellular barriers for effective transport. Herein we describe the synthesis of a series of novel, single-chain rigid cationic carotenoid lipids and a study of their preliminary in vitro...
Autores principales: | Pungente, Michael D., Jubeli, Emile, Øpstad, Christer L., Al-Kawaz, Mais, Barakat, Nour, Ibrahim, Tarek, Khalique, Nada Abdul, Raju, Liji, Jones, Rachel, Leopold, Philip L., Sliwka, Hans-Richard, Partali, Vassilia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268619/ https://www.ncbi.nlm.nih.gov/pubmed/22426529 http://dx.doi.org/10.3390/molecules17033484 |
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