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Xanthatin Induces Cell Cycle Arrest at G2/M Checkpoint and Apoptosis via Disrupting NF-κB Pathway in A549 Non-Small-Cell Lung Cancer Cells

Xanthatin, a natural sesquiterpene lactone, has significant antitumor activity against a variety of cancer cells, yet little is known about its anticancer mechanism. In this study, we demonstrated that xanthatin had obvious dose-/time-dependent cytotoxicity against the human non-small-cell lung canc...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Ruan, Junshan, Yan, Linggeng, Li, Weidong, Wu, Yu, Tao, Li, Zhang, Feng, Zheng, Shizhong, Wang, Aiyun, Lu, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268665/
https://www.ncbi.nlm.nih.gov/pubmed/22450683
http://dx.doi.org/10.3390/molecules17043736