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Xanthatin Induces Cell Cycle Arrest at G2/M Checkpoint and Apoptosis via Disrupting NF-κB Pathway in A549 Non-Small-Cell Lung Cancer Cells
Xanthatin, a natural sesquiterpene lactone, has significant antitumor activity against a variety of cancer cells, yet little is known about its anticancer mechanism. In this study, we demonstrated that xanthatin had obvious dose-/time-dependent cytotoxicity against the human non-small-cell lung canc...
Autores principales: | Zhang, Lei, Ruan, Junshan, Yan, Linggeng, Li, Weidong, Wu, Yu, Tao, Li, Zhang, Feng, Zheng, Shizhong, Wang, Aiyun, Lu, Yin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268665/ https://www.ncbi.nlm.nih.gov/pubmed/22450683 http://dx.doi.org/10.3390/molecules17043736 |
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