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Design, Synthesis and in Vivo Anti-inflammatory Activities of 2,4-Diaryl-5-4H-imidazolone Derivatives

A series of 2,4-diaryl-5(4H)-imidazolones were prepared and evaluated for their anti-inflammatory activities. Some selected 2,4-diaryl-5(4H)-imidazolones exhibited excellent anti-inflammatory activity in the carrageenan-induced rat paw edema model. Structure Activity Relationships within the series...

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Detalles Bibliográficos
Autores principales: El-Araby, Moustafa, Omar, Abdelsattar, Hassanein, Hassanein H., El-Helby, Abdel-Ghany H., Abdel-Rahman, Asharf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268676/
https://www.ncbi.nlm.nih.gov/pubmed/23079497
http://dx.doi.org/10.3390/molecules171012262