Chiral Bis(Imidazolidine)Pyridine-Cu Complex-Catalyzed Enantioselective [3+2]-Cycloaddition of Azomethine Imineswith Propiolates

[3+2] Cycloaddition of azomethine imines with electron-deficient terminal alkynes was smoothly catalyzed by a chiral bis(imidazolidine)pyridine-CuOAc complex to give bicyclic pyrazolo[1,2-a]pyrazolone derivatives with up to 74% ee.

Detalles Bibliográficos
Autores principales: Arai, Takayoshi, Ogino, Yuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268703/
https://www.ncbi.nlm.nih.gov/pubmed/22627972
http://dx.doi.org/10.3390/molecules17056170
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author Arai, Takayoshi
Ogino, Yuta
author_facet Arai, Takayoshi
Ogino, Yuta
author_sort Arai, Takayoshi
collection PubMed
description [3+2] Cycloaddition of azomethine imines with electron-deficient terminal alkynes was smoothly catalyzed by a chiral bis(imidazolidine)pyridine-CuOAc complex to give bicyclic pyrazolo[1,2-a]pyrazolone derivatives with up to 74% ee.
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spelling pubmed-62687032018-12-20 Chiral Bis(Imidazolidine)Pyridine-Cu Complex-Catalyzed Enantioselective [3+2]-Cycloaddition of Azomethine Imineswith Propiolates Arai, Takayoshi Ogino, Yuta Molecules Communication [3+2] Cycloaddition of azomethine imines with electron-deficient terminal alkynes was smoothly catalyzed by a chiral bis(imidazolidine)pyridine-CuOAc complex to give bicyclic pyrazolo[1,2-a]pyrazolone derivatives with up to 74% ee. MDPI 2012-05-24 /pmc/articles/PMC6268703/ /pubmed/22627972 http://dx.doi.org/10.3390/molecules17056170 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Communication
Arai, Takayoshi
Ogino, Yuta
Chiral Bis(Imidazolidine)Pyridine-Cu Complex-Catalyzed Enantioselective [3+2]-Cycloaddition of Azomethine Imineswith Propiolates
title Chiral Bis(Imidazolidine)Pyridine-Cu Complex-Catalyzed Enantioselective [3+2]-Cycloaddition of Azomethine Imineswith Propiolates
title_full Chiral Bis(Imidazolidine)Pyridine-Cu Complex-Catalyzed Enantioselective [3+2]-Cycloaddition of Azomethine Imineswith Propiolates
title_fullStr Chiral Bis(Imidazolidine)Pyridine-Cu Complex-Catalyzed Enantioselective [3+2]-Cycloaddition of Azomethine Imineswith Propiolates
title_full_unstemmed Chiral Bis(Imidazolidine)Pyridine-Cu Complex-Catalyzed Enantioselective [3+2]-Cycloaddition of Azomethine Imineswith Propiolates
title_short Chiral Bis(Imidazolidine)Pyridine-Cu Complex-Catalyzed Enantioselective [3+2]-Cycloaddition of Azomethine Imineswith Propiolates
title_sort chiral bis(imidazolidine)pyridine-cu complex-catalyzed enantioselective [3+2]-cycloaddition of azomethine imineswith propiolates
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268703/
https://www.ncbi.nlm.nih.gov/pubmed/22627972
http://dx.doi.org/10.3390/molecules17056170
work_keys_str_mv AT araitakayoshi chiralbisimidazolidinepyridinecucomplexcatalyzedenantioselective32cycloadditionofazomethineimineswithpropiolates
AT oginoyuta chiralbisimidazolidinepyridinecucomplexcatalyzedenantioselective32cycloadditionofazomethineimineswithpropiolates

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