Isostreptazolin and Sannaphenol, Two New Metabolites from Streptomyces sannanensis

Two new compounds, isostreptazolin (1) and sannaphenol (2), were isolated from the culture broth of Streptomyces sannanensis and their structures elucidated on the basis of 1D and 2D NMR as well as MS, IR and UV spectroscopic data analysis. The cytotoxic activity of 1 and 2 were evaluated. Both comp...

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Detalles Bibliográficos
Autores principales: Zheng, Dan, Han, Li, Li, Yiqing, Li, Jun, Rong, He, Leng, Qiao, Jiang, Yi, Zhao, Lixing, Huang, Xueshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268706/
https://www.ncbi.nlm.nih.gov/pubmed/22269869
http://dx.doi.org/10.3390/molecules17010836
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author Zheng, Dan
Han, Li
Li, Yiqing
Li, Jun
Rong, He
Leng, Qiao
Jiang, Yi
Zhao, Lixing
Huang, Xueshi
author_facet Zheng, Dan
Han, Li
Li, Yiqing
Li, Jun
Rong, He
Leng, Qiao
Jiang, Yi
Zhao, Lixing
Huang, Xueshi
author_sort Zheng, Dan
collection PubMed
description Two new compounds, isostreptazolin (1) and sannaphenol (2), were isolated from the culture broth of Streptomyces sannanensis and their structures elucidated on the basis of 1D and 2D NMR as well as MS, IR and UV spectroscopic data analysis. The cytotoxic activity of 1 and 2 were evaluated. Both compounds were inactive against H460 and HeLa cell lines at 100 μM.
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spelling pubmed-62687062018-12-11 Isostreptazolin and Sannaphenol, Two New Metabolites from Streptomyces sannanensis Zheng, Dan Han, Li Li, Yiqing Li, Jun Rong, He Leng, Qiao Jiang, Yi Zhao, Lixing Huang, Xueshi Molecules Article Two new compounds, isostreptazolin (1) and sannaphenol (2), were isolated from the culture broth of Streptomyces sannanensis and their structures elucidated on the basis of 1D and 2D NMR as well as MS, IR and UV spectroscopic data analysis. The cytotoxic activity of 1 and 2 were evaluated. Both compounds were inactive against H460 and HeLa cell lines at 100 μM. MDPI 2012-01-16 /pmc/articles/PMC6268706/ /pubmed/22269869 http://dx.doi.org/10.3390/molecules17010836 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Zheng, Dan
Han, Li
Li, Yiqing
Li, Jun
Rong, He
Leng, Qiao
Jiang, Yi
Zhao, Lixing
Huang, Xueshi
Isostreptazolin and Sannaphenol, Two New Metabolites from Streptomyces sannanensis
title Isostreptazolin and Sannaphenol, Two New Metabolites from Streptomyces sannanensis
title_full Isostreptazolin and Sannaphenol, Two New Metabolites from Streptomyces sannanensis
title_fullStr Isostreptazolin and Sannaphenol, Two New Metabolites from Streptomyces sannanensis
title_full_unstemmed Isostreptazolin and Sannaphenol, Two New Metabolites from Streptomyces sannanensis
title_short Isostreptazolin and Sannaphenol, Two New Metabolites from Streptomyces sannanensis
title_sort isostreptazolin and sannaphenol, two new metabolites from streptomyces sannanensis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268706/
https://www.ncbi.nlm.nih.gov/pubmed/22269869
http://dx.doi.org/10.3390/molecules17010836
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