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A Facile One-Pot Process for the Formation of Hindered Tertiary Amines

A simple and convenient method was developed for the preparation of hindered tertiary amines via direct reductive amination of ketones with secondary aryl amines, using trichlorosilane as reducing agent and tetramethylethylenediamine (TMEDA) as organic Lewis base activator. A broad range of ketones...

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Detalles Bibliográficos
Autores principales: Wang, Zhouyu, Pei, Dong, Zhang, Yu, Wang, Chao, Sun, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268708/
https://www.ncbi.nlm.nih.gov/pubmed/22555302
http://dx.doi.org/10.3390/molecules17055151

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