A New Cubitane Diterpenoid from the Soft Coral Sinularia crassa

A new cubitane diterpenoid, crassalone A (1), was isolated from the marine soft coral Sinularia crassa. The structure was determined by extensive spectroscopic analyses. Compound 1 is not cytotoxic (IC(50) > 20 μg/mL) toward the four human cancer cell lines tested (HL60, MDA-MB-231, HCT-116 and D...

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Detalles Bibliográficos
Autores principales: Cheng, Ching-Hsiao, Lin, Yun-Sheng, Wen, Zhi-Hong, Su, Jui-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268767/
https://www.ncbi.nlm.nih.gov/pubmed/22922278
http://dx.doi.org/10.3390/molecules170910072
Descripción
Sumario:A new cubitane diterpenoid, crassalone A (1), was isolated from the marine soft coral Sinularia crassa. The structure was determined by extensive spectroscopic analyses. Compound 1 is not cytotoxic (IC(50) > 20 μg/mL) toward the four human cancer cell lines tested (HL60, MDA-MB-231, HCT-116 and DLD-1).

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