A New Cubitane Diterpenoid from the Soft Coral Sinularia crassa

A new cubitane diterpenoid, crassalone A (1), was isolated from the marine soft coral Sinularia crassa. The structure was determined by extensive spectroscopic analyses. Compound 1 is not cytotoxic (IC(50) > 20 μg/mL) toward the four human cancer cell lines tested (HL60, MDA-MB-231, HCT-116 and D...

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Detalles Bibliográficos
Autores principales: Cheng, Ching-Hsiao, Lin, Yun-Sheng, Wen, Zhi-Hong, Su, Jui-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268767/
https://www.ncbi.nlm.nih.gov/pubmed/22922278
http://dx.doi.org/10.3390/molecules170910072
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author Cheng, Ching-Hsiao
Lin, Yun-Sheng
Wen, Zhi-Hong
Su, Jui-Hsin
author_facet Cheng, Ching-Hsiao
Lin, Yun-Sheng
Wen, Zhi-Hong
Su, Jui-Hsin
author_sort Cheng, Ching-Hsiao
collection PubMed
description A new cubitane diterpenoid, crassalone A (1), was isolated from the marine soft coral Sinularia crassa. The structure was determined by extensive spectroscopic analyses. Compound 1 is not cytotoxic (IC(50) > 20 μg/mL) toward the four human cancer cell lines tested (HL60, MDA-MB-231, HCT-116 and DLD-1).
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spelling pubmed-62687672018-12-12 A New Cubitane Diterpenoid from the Soft Coral Sinularia crassa Cheng, Ching-Hsiao Lin, Yun-Sheng Wen, Zhi-Hong Su, Jui-Hsin Molecules Communication A new cubitane diterpenoid, crassalone A (1), was isolated from the marine soft coral Sinularia crassa. The structure was determined by extensive spectroscopic analyses. Compound 1 is not cytotoxic (IC(50) > 20 μg/mL) toward the four human cancer cell lines tested (HL60, MDA-MB-231, HCT-116 and DLD-1). MDPI 2012-08-24 /pmc/articles/PMC6268767/ /pubmed/22922278 http://dx.doi.org/10.3390/molecules170910072 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Communication
Cheng, Ching-Hsiao
Lin, Yun-Sheng
Wen, Zhi-Hong
Su, Jui-Hsin
A New Cubitane Diterpenoid from the Soft Coral Sinularia crassa
title A New Cubitane Diterpenoid from the Soft Coral Sinularia crassa
title_full A New Cubitane Diterpenoid from the Soft Coral Sinularia crassa
title_fullStr A New Cubitane Diterpenoid from the Soft Coral Sinularia crassa
title_full_unstemmed A New Cubitane Diterpenoid from the Soft Coral Sinularia crassa
title_short A New Cubitane Diterpenoid from the Soft Coral Sinularia crassa
title_sort new cubitane diterpenoid from the soft coral sinularia crassa
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268767/
https://www.ncbi.nlm.nih.gov/pubmed/22922278
http://dx.doi.org/10.3390/molecules170910072
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