Synthesis and Cytotoxic Activity of Some Novel N-Pyridinyl-2-(6-phenylimidazo[2,1-b]thiazol-3-yl)acetamide Derivatives

A series of novel compounds bearing imidazo[2,1-b]thiazole scaffolds were designed and synthesized based on the optimization of the virtual screening hit compound N-(6-morpholinopyridin-3-yl)-2-(6-phenylimidazo[2,1-b]thiazol-3-yl)acetamide (5a), and tested for their cytotoxicity against human cancer...

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Detalles Bibliográficos
Autores principales: Ding, Huaiwei, Chen, Zhe, Zhang, Cunlong, Xin, Tian, Wang, Yini, Song, Hongrui, Jiang, Yuyang, Chen, Yuzong, Xu, Yongnan, Tan, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268833/
https://www.ncbi.nlm.nih.gov/pubmed/22525437
http://dx.doi.org/10.3390/molecules17044703

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