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Amplification and Re-Generation of LNA-Modified Libraries

Locked nucleic acids (LNA) confer high thermal stability and nuclease resistance to oligonucleotides. The discovery of polymerases that accept LNA triphosphates has led us to propose a scheme for the amplification and re-generation of LNA-containing oligonucleotide libraries. Such libraries could be...

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Detalles Bibliográficos
Autores principales:	Doessing, Holger, Hansen, Lykke H., Veedu, Rakesh N., Wengel, Jesper, Vester, Birte
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268865/ https://www.ncbi.nlm.nih.gov/pubmed/23128088 http://dx.doi.org/10.3390/molecules171113087

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