Hologram QSAR Models of 4-[(Diethylamino)methyl]-phenol Inhibitors of Acetyl/Butyrylcholinesterase Enzymes as Potential Anti-Alzheimer Agents

Hologram QSAR models were developed for a series of 36 inhibitors (29 training set and seven test set compounds) of acetyl/butyrylcholinesterase (AChE/BChE) enzymes, an attractive molecular target for Alzheimer’s disease (AD) treatment. The HQSAR models (N = 29) exhibited significant cross-validated...

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Detalles Bibliográficos
Autores principales: de Souza, Simone Decembrino, de Souza, Alessandra Mendonça Teles, de Sousa, Ana Carolina Corrêa, Sodero, Ana Carolina Rennó, Cabral, Lúcio Mendes, Albuquerque, Magaly Girão, Castro, Helena Carla, Rodrigues, Carlos Rangel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268868/
https://www.ncbi.nlm.nih.gov/pubmed/22878227
http://dx.doi.org/10.3390/molecules17089529

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