5'-Chloro-5'-deoxy-(±)-ENBA, a Potent and Selective Adenosine A(1) Receptor Agonist, Alleviates Neuropathic Pain in Mice Through Functional Glial and Microglial Changes without Affecting Motor or Cardiovascular Functions

This study was undertaken in order to investigate the effect of chronic treatment with 5′-chloro-5′-deoxy-(±)-ENBA, a potent and highly selective agonist of human adenosine A(1) receptor, on thermal hyperalgesia and mechanical allodynia in a mouse model of neuropathic pain, the Spared Nerve Injury (...

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Detalles Bibliográficos
Autores principales: Luongo, Livio, Petrelli, Riccardo, Gatta, Luisa, Giordano, Catia, Guida, Francesca, Vita, Patrizia, Franchetti, Palmarisa, Grifantini, Mario, de Novellis, Vito, Cappellacci, Loredana, Maione, Sabatino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268894/
https://www.ncbi.nlm.nih.gov/pubmed/23174891
http://dx.doi.org/10.3390/molecules171213712

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