Two New Diterpenoids from the Buds of Wikstroemia chamaedaphne

Two new diterpenoids, wikstroelide Q (1) and prostratin Q (5), together with three known diterpenoids, pimelea factors P(2) (2), P(3) (3), and prostratin (4), and five known lignans, (+)-epipioresinol (6), (+)-isolariciresinol (7), (−)-lariciresinol (8), (+)-epi-sesaminone (9), and prestegane B (10)...

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Detalles Bibliográficos
Autores principales: Guo, Jieru, Zhang, Jinwen, Shu, Penghua, Kong, Lingmei, Hao, Xincai, Xue, Yongbo, Luo, Zengwei, Li, Yan, Li, Gao, Yao, Guangmin, Zhang, Yonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268896/
https://www.ncbi.nlm.nih.gov/pubmed/22643353
http://dx.doi.org/10.3390/molecules17066424
Descripción
Sumario:Two new diterpenoids, wikstroelide Q (1) and prostratin Q (5), together with three known diterpenoids, pimelea factors P(2) (2), P(3) (3), and prostratin (4), and five known lignans, (+)-epipioresinol (6), (+)-isolariciresinol (7), (−)-lariciresinol (8), (+)-epi-sesaminone (9), and prestegane B (10), were isolated from the buds of Wikstroemia chamaedaphne Meissn. Their structures were elucidated by a combination of spectroscopic analyses. Compounds 1–10 were evaluated for their cytotoxicities against HL-60, SMMC-7721, A549, MCF-7, SW480, and BEAS-2B cell lines in vitro.

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