Two New Diterpenoids from the Buds of Wikstroemia chamaedaphne

Two new diterpenoids, wikstroelide Q (1) and prostratin Q (5), together with three known diterpenoids, pimelea factors P(2) (2), P(3) (3), and prostratin (4), and five known lignans, (+)-epipioresinol (6), (+)-isolariciresinol (7), (−)-lariciresinol (8), (+)-epi-sesaminone (9), and prestegane B (10)...

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Detalles Bibliográficos
Autores principales: Guo, Jieru, Zhang, Jinwen, Shu, Penghua, Kong, Lingmei, Hao, Xincai, Xue, Yongbo, Luo, Zengwei, Li, Yan, Li, Gao, Yao, Guangmin, Zhang, Yonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268896/
https://www.ncbi.nlm.nih.gov/pubmed/22643353
http://dx.doi.org/10.3390/molecules17066424
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author Guo, Jieru
Zhang, Jinwen
Shu, Penghua
Kong, Lingmei
Hao, Xincai
Xue, Yongbo
Luo, Zengwei
Li, Yan
Li, Gao
Yao, Guangmin
Zhang, Yonghui
author_facet Guo, Jieru
Zhang, Jinwen
Shu, Penghua
Kong, Lingmei
Hao, Xincai
Xue, Yongbo
Luo, Zengwei
Li, Yan
Li, Gao
Yao, Guangmin
Zhang, Yonghui
author_sort Guo, Jieru
collection PubMed
description Two new diterpenoids, wikstroelide Q (1) and prostratin Q (5), together with three known diterpenoids, pimelea factors P(2) (2), P(3) (3), and prostratin (4), and five known lignans, (+)-epipioresinol (6), (+)-isolariciresinol (7), (−)-lariciresinol (8), (+)-epi-sesaminone (9), and prestegane B (10), were isolated from the buds of Wikstroemia chamaedaphne Meissn. Their structures were elucidated by a combination of spectroscopic analyses. Compounds 1–10 were evaluated for their cytotoxicities against HL-60, SMMC-7721, A549, MCF-7, SW480, and BEAS-2B cell lines in vitro.
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spelling pubmed-62688962018-12-12 Two New Diterpenoids from the Buds of Wikstroemia chamaedaphne Guo, Jieru Zhang, Jinwen Shu, Penghua Kong, Lingmei Hao, Xincai Xue, Yongbo Luo, Zengwei Li, Yan Li, Gao Yao, Guangmin Zhang, Yonghui Molecules Article Two new diterpenoids, wikstroelide Q (1) and prostratin Q (5), together with three known diterpenoids, pimelea factors P(2) (2), P(3) (3), and prostratin (4), and five known lignans, (+)-epipioresinol (6), (+)-isolariciresinol (7), (−)-lariciresinol (8), (+)-epi-sesaminone (9), and prestegane B (10), were isolated from the buds of Wikstroemia chamaedaphne Meissn. Their structures were elucidated by a combination of spectroscopic analyses. Compounds 1–10 were evaluated for their cytotoxicities against HL-60, SMMC-7721, A549, MCF-7, SW480, and BEAS-2B cell lines in vitro. MDPI 2012-05-29 /pmc/articles/PMC6268896/ /pubmed/22643353 http://dx.doi.org/10.3390/molecules17066424 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Guo, Jieru
Zhang, Jinwen
Shu, Penghua
Kong, Lingmei
Hao, Xincai
Xue, Yongbo
Luo, Zengwei
Li, Yan
Li, Gao
Yao, Guangmin
Zhang, Yonghui
Two New Diterpenoids from the Buds of Wikstroemia chamaedaphne
title Two New Diterpenoids from the Buds of Wikstroemia chamaedaphne
title_full Two New Diterpenoids from the Buds of Wikstroemia chamaedaphne
title_fullStr Two New Diterpenoids from the Buds of Wikstroemia chamaedaphne
title_full_unstemmed Two New Diterpenoids from the Buds of Wikstroemia chamaedaphne
title_short Two New Diterpenoids from the Buds of Wikstroemia chamaedaphne
title_sort two new diterpenoids from the buds of wikstroemia chamaedaphne
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268896/
https://www.ncbi.nlm.nih.gov/pubmed/22643353
http://dx.doi.org/10.3390/molecules17066424
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