Towards Recyclable NAD(P)H Regeneration Catalysts

Rh(III)-TsDPEN, an immobilized analog of the well-known [Cp*Rh(bpy)(H(2)O)](2+) was evaluated as a heterogeneous, recyclable regeneration catalyst for reduced oxidoreductase cofactors [NAD(P)H]. Repeated use of this catalyst was established and the catalytic properties were initially investigated. A...

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Detalles Bibliográficos
Autores principales: de Torres, Miriam, Dimroth, Jonas, Arends, Isabel W. C. E., Keilitz, Juliane, Hollmann, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268897/
https://www.ncbi.nlm.nih.gov/pubmed/22895028
http://dx.doi.org/10.3390/molecules17089835
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author de Torres, Miriam
Dimroth, Jonas
Arends, Isabel W. C. E.
Keilitz, Juliane
Hollmann, Frank
author_facet de Torres, Miriam
Dimroth, Jonas
Arends, Isabel W. C. E.
Keilitz, Juliane
Hollmann, Frank
author_sort de Torres, Miriam
collection PubMed
description Rh(III)-TsDPEN, an immobilized analog of the well-known [Cp*Rh(bpy)(H(2)O)](2+) was evaluated as a heterogeneous, recyclable regeneration catalyst for reduced oxidoreductase cofactors [NAD(P)H]. Repeated use of this catalyst was established and the catalytic properties were initially investigated. Apparently, Rh(III)-TsDPEN is prone to severe diffusion limitations, necessitating further developments. Overall, a promising concept for chemoenzymatic redox catalysis is proposed, which may overcome some of the current limitations such as catalyst cost and incompatibility of Rh with some biocatalysts.
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spelling pubmed-62688972018-12-12 Towards Recyclable NAD(P)H Regeneration Catalysts de Torres, Miriam Dimroth, Jonas Arends, Isabel W. C. E. Keilitz, Juliane Hollmann, Frank Molecules Communication Rh(III)-TsDPEN, an immobilized analog of the well-known [Cp*Rh(bpy)(H(2)O)](2+) was evaluated as a heterogeneous, recyclable regeneration catalyst for reduced oxidoreductase cofactors [NAD(P)H]. Repeated use of this catalyst was established and the catalytic properties were initially investigated. Apparently, Rh(III)-TsDPEN is prone to severe diffusion limitations, necessitating further developments. Overall, a promising concept for chemoenzymatic redox catalysis is proposed, which may overcome some of the current limitations such as catalyst cost and incompatibility of Rh with some biocatalysts. MDPI 2012-08-15 /pmc/articles/PMC6268897/ /pubmed/22895028 http://dx.doi.org/10.3390/molecules17089835 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Communication
de Torres, Miriam
Dimroth, Jonas
Arends, Isabel W. C. E.
Keilitz, Juliane
Hollmann, Frank
Towards Recyclable NAD(P)H Regeneration Catalysts
title Towards Recyclable NAD(P)H Regeneration Catalysts
title_full Towards Recyclable NAD(P)H Regeneration Catalysts
title_fullStr Towards Recyclable NAD(P)H Regeneration Catalysts
title_full_unstemmed Towards Recyclable NAD(P)H Regeneration Catalysts
title_short Towards Recyclable NAD(P)H Regeneration Catalysts
title_sort towards recyclable nad(p)h regeneration catalysts
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268897/
https://www.ncbi.nlm.nih.gov/pubmed/22895028
http://dx.doi.org/10.3390/molecules17089835
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