Phytoecdysteroids from the Roots of Achyranthes bidentata Blume

Two new phytoecdysteroids, (25S)-20,22-O-(R-ethylidene)inokosterone (1) and 20,22-O-(R-3-methoxycarbonyl)propylidene-20-hydroxyecdysone (2), together with six known phytoecdysteroids 3–8 were isolated from the roots of Achyranthes bidentata Blume. The new structures were established on the basis of...

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Detalles Bibliográficos
Autores principales: Zhang, Mei, Zhou, Zhong-Yu, Wang, Jing, Cao, Yong, Chen, Xue-Xiang, Zhang, Wei-Min, Lin, Li-Dong, Tan, Jian-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268906/
https://www.ncbi.nlm.nih.gov/pubmed/22418932
http://dx.doi.org/10.3390/molecules17033324
Descripción
Sumario:Two new phytoecdysteroids, (25S)-20,22-O-(R-ethylidene)inokosterone (1) and 20,22-O-(R-3-methoxycarbonyl)propylidene-20-hydroxyecdysone (2), together with six known phytoecdysteroids 3–8 were isolated from the roots of Achyranthes bidentata Blume. The new structures were established on the basis of spectroscopic studies and chemical evidences. The absolute configuration at C-25 in the structure of known compound 3 was determined by chemical and spectroscopic means.

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