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The Effect of β-Carotene Supplementation on the Pharmacokinetics of Nelfinavir and Its Active Metabolite M8 in HIV-1-infected Patients
β-Carotene supplements are often taken by individuals living with HIV-1. Contradictory results from in vitro studies suggest that β-carotene may inhibit or induce cytochrome P450 enzymes and transporters. The study objective was to investigate the effect of β-carotene on the steady-state pharmacokin...
Autores principales: | Sheehan, Nancy L., van Heeswijk, Rolf P. G., Foster, Brian C., Akhtar, Humayoun, Singhal, Neera, Seguin, Isabelle, DelBalso, Lina, Bourbeau, Marc, Chauhan, Bobby M., Boulassel, Mohammed-Rachid, Burger, David M., Lalonde, Richard G., Cameron, Donald William |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268962/ https://www.ncbi.nlm.nih.gov/pubmed/22241465 http://dx.doi.org/10.3390/molecules17010688 |
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