GHGKHKNK Octapeptide (P-5m) Inhibits Metastasis of HCCLM3 Cell Lines via Regulation of MMP-2 Expression in in Vitro and in Vivo Studies

P-5m, an octapeptide derived from domain 5 of HKa, was initially found to inhibit the invasion and migration of melanoma cells. The high metastatic potential of melanoma cells was prevented by the HGK motif in the P-5m peptide in vitro and in an experimental lung metastasis model, suggesting that P-...

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Detalles Bibliográficos
Autores principales: Han, Xiao, Yan, Dong-Mei, Zhao, Xiang-Feng, Hiroshi, Matsuura, Ding, Wei-Guang, Li, Peng, Jiang, Shuang, Du, Bai-Rong, Du, Pei-Ge, Zhu, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268966/
https://www.ncbi.nlm.nih.gov/pubmed/22395332
http://dx.doi.org/10.3390/molecules17021357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268966/
https://www.ncbi.nlm.nih.gov/pubmed/22395332
http://dx.doi.org/10.3390/molecules17021357

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