Bioactive Phenolic Amides from Celtisafricana

Nine compounds have been isolated for the first time from Celtis africana, namely trans-N-coumaroyltyramine (1), trans-N-feruloyltyramine (2), trans-N-caffeoyltyramine (3), lauric acid (4), oleic acid (5), palmitic acid (6), lupeol (7), β-sitosterol (8) and oleanolic acid (9), respectively. Their st...

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Autores principales: Al-Taweel, Areej Mohammad, Perveen, Shagufta, El-Shafae, Azza Muhammed, Fawzy, Ghada Ahmed, Malik, Abdul, Afza, Nighat, Iqbal, Lubna, Latif, Mehreen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268968/
https://www.ncbi.nlm.nih.gov/pubmed/22391601
http://dx.doi.org/10.3390/molecules17032675
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author Al-Taweel, Areej Mohammad
Perveen, Shagufta
El-Shafae, Azza Muhammed
Fawzy, Ghada Ahmed
Malik, Abdul
Afza, Nighat
Iqbal, Lubna
Latif, Mehreen
author_facet Al-Taweel, Areej Mohammad
Perveen, Shagufta
El-Shafae, Azza Muhammed
Fawzy, Ghada Ahmed
Malik, Abdul
Afza, Nighat
Iqbal, Lubna
Latif, Mehreen
author_sort Al-Taweel, Areej Mohammad
collection PubMed
description Nine compounds have been isolated for the first time from Celtis africana, namely trans-N-coumaroyltyramine (1), trans-N-feruloyltyramine (2), trans-N-caffeoyltyramine (3), lauric acid (4), oleic acid (5), palmitic acid (6), lupeol (7), β-sitosterol (8) and oleanolic acid (9), respectively. Their structures have been elucidated by different spectroscopic techniques. The isolated compounds were screened for their antioxidant, anti-inflammatory and acetylcholinestrease enzyme inhibitory activities. Compounds 1–3 showed significant antioxidant and anti-inflammatory activities and weak to moderate acetylcholinestrease enzyme inhibition activity.
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spelling pubmed-62689682018-12-20 Bioactive Phenolic Amides from Celtisafricana Al-Taweel, Areej Mohammad Perveen, Shagufta El-Shafae, Azza Muhammed Fawzy, Ghada Ahmed Malik, Abdul Afza, Nighat Iqbal, Lubna Latif, Mehreen Molecules Article Nine compounds have been isolated for the first time from Celtis africana, namely trans-N-coumaroyltyramine (1), trans-N-feruloyltyramine (2), trans-N-caffeoyltyramine (3), lauric acid (4), oleic acid (5), palmitic acid (6), lupeol (7), β-sitosterol (8) and oleanolic acid (9), respectively. Their structures have been elucidated by different spectroscopic techniques. The isolated compounds were screened for their antioxidant, anti-inflammatory and acetylcholinestrease enzyme inhibitory activities. Compounds 1–3 showed significant antioxidant and anti-inflammatory activities and weak to moderate acetylcholinestrease enzyme inhibition activity. MDPI 2012-03-05 /pmc/articles/PMC6268968/ /pubmed/22391601 http://dx.doi.org/10.3390/molecules17032675 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Al-Taweel, Areej Mohammad
Perveen, Shagufta
El-Shafae, Azza Muhammed
Fawzy, Ghada Ahmed
Malik, Abdul
Afza, Nighat
Iqbal, Lubna
Latif, Mehreen
Bioactive Phenolic Amides from Celtisafricana
title Bioactive Phenolic Amides from Celtisafricana
title_full Bioactive Phenolic Amides from Celtisafricana
title_fullStr Bioactive Phenolic Amides from Celtisafricana
title_full_unstemmed Bioactive Phenolic Amides from Celtisafricana
title_short Bioactive Phenolic Amides from Celtisafricana
title_sort bioactive phenolic amides from celtisafricana
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268968/
https://www.ncbi.nlm.nih.gov/pubmed/22391601
http://dx.doi.org/10.3390/molecules17032675
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