An ent-Kaurane-Type Diterpene in Croton antisyphiliticus Mart.

Croton antisyphiliticus is a medicinal plant widely used in the treatment of microbial infections, especially those affecting the genital tract. Crude extract, fractions and pure compound isolated from roots of this species were investigated to validate their antimicrobial activity against Escherich...

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Detalles Bibliográficos
Autores principales: Pereira, Sarazete, Taleb-Contini, Silvia, Coppede, Juliana, Pereira, Paulo, Bertoni, Bianca, França, Suzelei, Pereira, Ana Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268975/
https://www.ncbi.nlm.nih.gov/pubmed/22832886
http://dx.doi.org/10.3390/molecules17088851
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author Pereira, Sarazete
Taleb-Contini, Silvia
Coppede, Juliana
Pereira, Paulo
Bertoni, Bianca
França, Suzelei
Pereira, Ana Maria
author_facet Pereira, Sarazete
Taleb-Contini, Silvia
Coppede, Juliana
Pereira, Paulo
Bertoni, Bianca
França, Suzelei
Pereira, Ana Maria
author_sort Pereira, Sarazete
collection PubMed
description Croton antisyphiliticus is a medicinal plant widely used in the treatment of microbial infections, especially those affecting the genital tract. Crude extract, fractions and pure compound isolated from roots of this species were investigated to validate their antimicrobial activity against Escherichia coli and Staphylococcus aureus. The compound ent-kaur-16-en-18-oic acid was isolated as a major component (0.7% of crude extract), and its MIC value determined against S. aureus (ATCC 6538) was 250 μg/mL. This is the first phytochemical work on the species monitored with antimicrobial assay.
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spelling pubmed-62689752018-12-12 An ent-Kaurane-Type Diterpene in Croton antisyphiliticus Mart. Pereira, Sarazete Taleb-Contini, Silvia Coppede, Juliana Pereira, Paulo Bertoni, Bianca França, Suzelei Pereira, Ana Maria Molecules Article Croton antisyphiliticus is a medicinal plant widely used in the treatment of microbial infections, especially those affecting the genital tract. Crude extract, fractions and pure compound isolated from roots of this species were investigated to validate their antimicrobial activity against Escherichia coli and Staphylococcus aureus. The compound ent-kaur-16-en-18-oic acid was isolated as a major component (0.7% of crude extract), and its MIC value determined against S. aureus (ATCC 6538) was 250 μg/mL. This is the first phytochemical work on the species monitored with antimicrobial assay. MDPI 2012-07-25 /pmc/articles/PMC6268975/ /pubmed/22832886 http://dx.doi.org/10.3390/molecules17088851 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Pereira, Sarazete
Taleb-Contini, Silvia
Coppede, Juliana
Pereira, Paulo
Bertoni, Bianca
França, Suzelei
Pereira, Ana Maria
An ent-Kaurane-Type Diterpene in Croton antisyphiliticus Mart.
title An ent-Kaurane-Type Diterpene in Croton antisyphiliticus Mart.
title_full An ent-Kaurane-Type Diterpene in Croton antisyphiliticus Mart.
title_fullStr An ent-Kaurane-Type Diterpene in Croton antisyphiliticus Mart.
title_full_unstemmed An ent-Kaurane-Type Diterpene in Croton antisyphiliticus Mart.
title_short An ent-Kaurane-Type Diterpene in Croton antisyphiliticus Mart.
title_sort ent-kaurane-type diterpene in croton antisyphiliticus mart.
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268975/
https://www.ncbi.nlm.nih.gov/pubmed/22832886
http://dx.doi.org/10.3390/molecules17088851
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