Cargando…

A Facile Solvent Free Claisen-Schmidt Reaction: Synthesis of α,α′-bis-(Substituted-benzylidene)cycloalkanones and α,α′-bis-(Substituted-alkylidene)cycloalkanones

Solvent-free Claisen-Schmidt reactions of cycloalkanones with various substituted benzaldehydes (aryl aldehydes) using solid NaOH (20 mol%) and applying a grinding technique were studied. Quantitative yields (96–98%) of α,α'-bis-(substituted-benzylidene)cycloalkanones were obtained. Aliphatic a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rahman, A. F. M. Motiur, Ali, Roushown, Jahng, Yurngdong, Kadi, Adnan A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269007/ https://www.ncbi.nlm.nih.gov/pubmed/22231494 http://dx.doi.org/10.3390/molecules17010571

Ejemplares similares

Theoretical Study of Structure and Photophysics of Homologous Series of Bis(arylydene)cycloalkanones
por: Starostin, Roman O., et al.
Publicado: (2023)

A Facile Synthesis of New 2-Amino-4H-pyran-3-carbonitriles by a One-Pot Reaction of α, α′-Bis(arylidene) Cycloalkanones and Malononitrile in the Presence of K(2)CO(3)
por: Karimi-Jaberi, Zahed, et al.
Publicado: (2012)

Directing the Stereoselectivity of the Claisen Rearrangement to Form Cyclic Ketones with Full Substitution at the α-Positions
por: Badmus, Fatimat O., et al.
Publicado: (2023)

Photoredox-enabled 1,2-dialkylation of α-substituted acrylates via Ireland–Claisen rearrangement
por: Kleinmans, Roman, et al.
Publicado: (2021)

Ultrasonic Studies on Molecular Interactions in Binary Mixtures of N-Methyl Aniline with Methyl Isobutylketone, +3-Pentanone, and +Cycloalkanones at 303.15 K
por: Gowrisankar, M., et al.
Publicado: (2013)

Acid catalyzed one-pot approach towards the synthesis of curcuminoid systems: unsymmetrical diarylidene cycloalkanones, exploration of their single crystals, optical and nonlinear optical properties
por: Ali, Akbar, et al.
Publicado: (2023)

Stereoselective α-fluoroamide and α-fluoro-γ-lactone synthesis by an asymmetric zwitterionic aza-Claisen rearrangement
por: Tenza, Kenny, et al.
Publicado: (2005)

The Synthesis and Herbicidal Activity of 1-Alkyl-3-(α-hydroxy-substituted benzylidene)pyrrolidine-2,4-diones
por: Zhu, You-Quan, et al.
Publicado: (2005)

Novel N′-substituted benzylidene benzohydrazides linked to 1,2,3-triazoles: potent α-glucosidase inhibitors
por: Saeedi, Mina, et al.
Publicado: (2023)

Synthesis of highly substituted allenylsilanes by alkylidenation of silylketenes
por: Marsden, Stephen P, et al.
Publicado: (2005)

New MgFeAl-LDH Catalysts for Claisen–Schmidt Condensation
por: Zăvoianu, Rodica, et al.
Publicado: (2022)

Activation of human α-carbonic anhydrase isoforms I, II, IV and VII with bis-histamine schiff bases and bis-spinaceamine substituted derivatives
por: Akocak, Suleyman, et al.
Publicado: (2019)

Coupling of α,α-difluoro-substituted organozinc reagents with 1-bromoalkynes
por: Zemtsov, Artem A, et al.
Publicado: (2015)

Switchable π-electronic network of bis(α-oligothienyl)-substituted hexaphyrins between helical versus rectangular circuit
por: Oh, Juwon, et al.
Publicado: (2016)

An efficient and selective microwave-assisted Claisen-Schmidt reaction for the synthesis of functionalized benzalacetones
por: Rayar, Anita, et al.
Publicado: (2015)

Synthesis of Benzylidene Analogs of Oleanolic Acid as Potential α-Glucosidase and α-Amylase Inhibitors
por: Ke, Jun-Jie, et al.
Publicado: (2022)

Facile Synthesis of Bis(indolyl)methanes Catalyzed by α-Chymotrypsin
por: Xie, Zong-Bo, et al.
Publicado: (2014)

Galeon: A Biologically Active Molecule with In Silico Metabolite Prediction, In Vitro Metabolic Profiling in Rat Liver Microsomes, and In Silico Binding Mechanisms with CYP450 Isoforms
por: Rahman, A. F. M. Motiur, et al.
Publicado: (2020)

Synthesis of Substituted α-Trifluoromethyl Piperidinic Derivatives
por: Rioton, Sarah, et al.
Publicado: (2017)

Asymmetric vinylogous aldol addition of alkylidene oxindoles on trifluoromethyl-α,β-unsaturated ketones
por: Crotti, Simone, et al.
Publicado: (2018)

5,20-Bis(α-oligothienyl)-substituted [26]hexaphyrins possessing electronic circuits strongly perturbed by meso-oligothienyl substituents
por: Mori, Hirotaka, et al.
Publicado: (2015)

Highly efficient one-step microwave-assisted synthesis of structurally diverse bis-substituted α-amino acid derived diimides
por: Konopka, Marcin, et al.
Publicado: (2018)

Facile Synthesis of 3-Substituted Thiazolo[2,3-α]tetrahydroisoquinolines
por: Huang, Sheng-Han, et al.
Publicado: (2021)

Investigation into the Thermal Response and Pharmacological Activity of Substituted Schiff Bases on α-Amylase and α-Glucosidase
por: Okoli, Bamidele Joseph, et al.
Publicado: (2018)

α-Functionally Substituted α,β-Unsaturated Aldehydes as Fine Chemicals Reagents: Synthesis and Application
por: Verochkina, Ekaterina A., et al.
Publicado: (2021)

Diastereo- and enantioselective additions of α-nitro esters to imines for anti-α,β-diamino acid synthesis with α-alkyl-substitution
por: Sprague, Daniel J., et al.
Publicado: (2018)

Pd‐Catalyzed Allylation of Imines to Access α‐CF(3)‐Substituted α‐Amino Acid Derivatives
por: Winter, Michael, et al.
Publicado: (2019)

Synthesis and Molecular Docking Studies of Alkoxy- and Imidazole-Substituted Xanthones as α-Amylase and α-Glucosidase Inhibitors
por: Aguila-Muñoz, Dolores G., et al.
Publicado: (2023)

Organocatalytic Enantioselective α-Nitrogenation of α,α-Disubstituted Aldehydes in the Absence of a Solvent
por: Torregrosa-Chinillach, Alejandro, et al.
Publicado: (2022)

Synthesis of Optically and Redox Active Polyenaminones from Diamines and α,α’-Bis[(dimethylamino)methylidene]cyclohexanediones
por: Štanfel, Urša, et al.
Publicado: (2022)

Reactivities of Substituted α-Phenyl-N-tert-butyl Nitrones
por: Rosselin, Marie, et al.
Publicado: (2014)

Aluminacyclopentanes in the synthesis of 3-substituted phospholanes and α,ω-bisphospholanes
por: D’yakonov, Vladimir A, et al.
Publicado: (2016)

Elimination of oxygen sensitivity in α-titanium by substitutional alloying with Al
por: Chong, Yan, et al.
Publicado: (2021)

Organocatalytic asymmetric nitroso aldol reaction of α-substituted malonamates
por: Gupta, Ekta, et al.
Publicado: (2022)

Distal meta-C–H functionalization of α-substituted cinnamates
por: Bakthadoss, Manickam, et al.
Publicado: (2023)

A green synthesis approach toward large-scale production of benzalacetone via Claisen–Schmidt condensation
por: Sun, Ruolun, et al.
Publicado: (2022)

Synthesis of propenone-linked covalent organic frameworks via Claisen-Schmidt reaction for photocatalytic removal of uranium
por: Niu, Cheng-Peng, et al.
Publicado: (2023)

Phosphine-catalyzed [3 + 2] annulation of β-sulfonamido-substituted enones with trans-α-cyano-α,β-unsaturated ketones for the synthesis of highly substituted pyrrolidines
por: Gao, Zhenzhen, et al.
Publicado: (2021)

Catalysis of linear alkene metathesis by Grubbs-type ruthenium alkylidene complexes containing hemilabile α,α-diphenyl-(monosubstituted-pyridin-2-yl)methanolato ligands
por: Tole, Tegene T, et al.
Publicado: (2019)

Efficient 1,4-addition of α-substituted fluoro(phenylsulfonyl)methane derivatives to α,β-unsaturated compounds
por: Prakash, G K Surya, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_okh1jd2gfrgl4rcgh1sgf3t2b7