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An Efficient Synthesis of Novel Dispirooxindole Derivatives via One-Pot Three-Component 1,3-Dipolar Cycloaddition Reactions

A series of novel dispirooxindoles have been synthesized through three-component 1,3-dipolar cycloaddition of azomethine ylides generated in situ by the decarboxylative condensation of isatin and an α-amino acid with the dipolarophile 5-benzylidene-1,3-dimethylpyrimidine-2,4,6-trione. This method ha...

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Detalles Bibliográficos
Autores principales:	Huang, Zhibin, Zhao, Qian, Chen, Gang, Wang, Huiyuan, Lin, Wei, Xu, Lexing, Liu, Hongtao, Wang, Juxian, Shi, Daqing, Wang, Yucheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269013/ https://www.ncbi.nlm.nih.gov/pubmed/23103534 http://dx.doi.org/10.3390/molecules171112704

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